RESEARCH AND ACADEMICS

National Center for Rheumatic Diseases (NCRD) is a stand-alone center dedicated to the care of rheumatic patients. It also provides services related to Neurology, Dermatology, Nephrology, Orthopedics, Physiotherapy, Dietetics and Dentistry. In addition to providing clinical care for the patient, the center has also developed a strong department dedicated to research. The research department has been keeping systematic data on various rheumatic diseases, including the presentation, risk-factors, laboratory and clinical features and treatment outcomes.
Currently, NCRD is conducting five researches approved by Nepal Health Research Council (NHRC), the central governing body for monitoring medical researches in Nepal.
  1. Efficacy and safety of tapering dose of adalimumab in patients with Ankylosing Spondylitis
  2. National program for control of Rheumatic Diseases (Nat-CORD based epidemiological survey for musculoskeletal diseases in rural and urban areas in hilly and Terai region in Nepal.
  3. Long term treatment outcome in Rheumatoid Arthritis: a single center prospective study.
  4. Efficacy and tolerance of aceclofenac and diacerin combination for inflammatory osteoarthritis- A single center observational study.
  5. Long term outcome of undifferentiated arthritis: A prospective cohort study.
Also, few researches conducted at NCRD are published and few are under process of publication in different national and international journals.
  1. Early Undifferentiated Arthritis: A Developing Country Perspective from Nepal. Journal of Nepal Medical Association. 2018
http://jnma.com.np/jnma/index.php/jnma/article/view/3893/2819
  1. Sustained Drug Free Remission of Lupus Panniculitis with Methotrexate: A Case Report From Nepal. Journal of Nepal Medical Association. 2018
http://jnma.com.np/jnma/index.php/jnma/article/view/3885/2825
  1. Synovial fluid uric acid level aids diagnosis of gout. Biomedical Reports 2018
https://www.ncbi.nlm.nih.gov/pubmed/29930806
  1. Efficacy of high dose vitamin D supplementation in improving serum 25-hydroxyvitamin D among laboratory personnel working at the Nepal National Center for Rheumatic Diseases. Biomedical Reports. 2017
https://www.ncbi.nlm.nih.gov/pubmed/29188059
  1. Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology. 2017
https://www.ncbi.nlm.nih.gov/pubmed/27995382
  1. Inflammatory variant of pachydermoperiostosis responding to methotrexate: A report of two cases. Oxford Medical Case Reports. Accepted for publication 2019
UNDER REVIEW RESEARCHES
  1. Study of metabolic parameters in gout: A single center study.
  2. Clinicodemographic profile of patients with undifferentiated arthritis.
  3. Translation and validation of Health Assessment Questionnaire in Nepali.
  4. Translation and validation of WOMAC in Nepali.
  5. Study of anthropometric parameters in patients with rheumatoid arthritis: THESIS of Ms. Prajwola Prajapati
  6. Simultaneous initiation of anti-tubercular treatment with adalimumab in latent tuberculosis positive patients
ONGOING STUDIES/RESEARCH
  1. Effect of intermittent calorie restriction in BMI
  2. Clinical profile of Psoriatic arthritis patients.
  3. Clinical use and findings of musculoskeletal ultrasound.
  4. Diagnosis of Latent Tubercular infection
In addition, NCRD is also conducting community-based surveys related to the risk-factors, diagnosis and treatment of various rheumatic conditions. We at NCRD can accommodate students from Bachelor in Public Health (BPH) and Bachelor in Pharmacy (B Pharm) interested in conducting clinical thesis as a part of their curriculum.