RESEARCH AND ACADEMICS

National Center for Rheumatic Diseases (NCRD) is a stand-alone center dedicated to the care of rheumatic patients. It also provides services related to Neurology, Dermatology, Nephrology, Orthopedics, Physiotherapy, Dietetics and Dentistry. In addition to providing clinical care for the patient, the center has also developed a strong department dedicated to research. The research department has been keeping systematic data on various rheumatic diseases, including the presentation, risk-factors, laboratory and clinical features and treatment outcomes.
research1
Currently, NCRD is conducting five researches approved by Nepal Health Research Council (NHRC), the central governing body for monitoring medical researches in Nepal.

  1. Efficacy and safety of tapering dose of adalimumab in patients with Ankylosing Spondylitis
  2. National program for control of Rheumatic Diseases (Nat-CORD based epidemiological survey for musculoskeletal diseases in rural and urban areas in hilly and Terai region in Nepal.
  3. Long term treatment outcome in Rheumatoid Arthritis: a single center prospective study.
  4. Efficacy and tolerance of aceclofenac and diacerin combination for inflammatory osteoarthritis- A single center observational study.
  5. Long term outcome of undifferentiated arthritis: A prospective cohort study.

research2

NCRD is also conducting community-based surveys related to the risk-factors, diagnosis and treatment of various rheumatic conditions. We at NCRD can accommodate students from Bachelor in Public Health (BPH) and Bachelor in Pharmacy (B Pharm) interested in conducting clinical thesis as a part of their curriculum.

Also, few researches conducted at NCRD are published and few are under process of publication in different national and international journals.

  1. Early Undifferentiated Arthritis: A Developing Country Perspective from Nepal. Journal of Nepal Medical Association. 2018

        http://jnma.com.np/jnma/index.php/jnma/article/view/3893/2819

  1. Sustained Drug Free Remission of Lupus Panniculitis with Methotrexate: A Case Report From Nepal. Journal of Nepal Medical Association. 2018

          http://jnma.com.np/jnma/index.phpnma/article/view/3885/2825

  1. Synovial fluid uric acid level aids diagnosis of gout. Biomedical Reports 2018

          https://www.ncbi.nlm.nih.gov/pubmed/29930806

  1. Efficacy of high dose vitamin D supplementation in improving serum 25-hydroxyvitamin D among laboratory personnel working at the Nepal National Center for Rheumatic Diseases. Biomedical Reports. 2017

         https://www.ncbi.nlm.nih.gov/pubmed/29188059

  1. Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology. 2017

          https://www.ncbi.nlm.nih.gov/pubmed/27995382

  1. Inflammatory variant of pachydermoperiostosis responding to methotrexate: A report of two cases. Oxford Medical Case Reports. Accepted for publication 2019
  1.  Changes in Urinary Microalbumin Levels after Correction of Hyperuricemia in Patients with Gout: An Observational Cohort Study : 2020

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152934/
DOI: https://doi.org/10.1155/2020/8310685

  1. Efficacy of Vitamin E in Methotrexate-Induced Hepatotoxicity in Rheumatoid Arthritis: An Open-Label Case-Control Study :2020

Link: https://www.hindawi.com/journals/ijr/2020/5723485/
DOI: https://doi.org/10.1155/2020/5723485

  1. Translation, Cross-Cultural Adaptation And Validation Of Nepali Version Of Health Assessment Questionnaire-Disability Index In Rheumatoid Arthritis Patients From Nepal. : 2019

Link:https://www.ncbi.nlm.nih.gov/pubmed/31342648/?utm_source=gquery&utm_medium=referral&utm_campaign=CitationSensor
DOI: https://doi.org/10.1111/1756-185X.13670

  1. Translation, validation and cross-cultural adaptation of the Nepali version of WOMAC® LK 3.1. : 2019

Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Translation%2C+validation+and+cross-cultural+adaptation+of+the+Nepali+version+of+WOMAC%C2%AE+LK+3.1.
DOI: https://doi.org/10.1111/1756-185X.13690

  1. Simultaneous Adalimumab and Antitubercular Treatment for Latent Tubercular Infection: An Experience from Nepal: 2019

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463559/
DOI: https://doi.org/10.1155/2019/2034950

  1. Vitamin D in Rheumatic Diseases: Interpretation and Significance : 2019

Link: https://www.researchgate.net/publication/335106702_Vitamin_D_in_Rheumatic_Diseases_Interpretation_and_Significance
DOI: https://doi.org/10.5772/intechopen.88677

  1. A Simplified Understanding of the Black Swan: Anti-phospholipid Antibody Syndrome :2019

Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=A+Simplified+Understanding+of+the+Black+Swan%3A+Anti-phospholipid+Antibody+Syndrome
DOI:  https://doi.org/10.31729/jnma.4226

  1. Prevalence and pattern of dyslipidemias in patients with active rheumatic diseases :2018

Link: https://www.researchgate.net/publication/279168396_Prevalence_and_pattern_of_dyslipidemias_in_patients_with_active_rheumatic_diseases

  1. Nailfold capillaroscopic findings in patients with Raynaud’s phenomenon: Preliminary report : 2015

Link: https://www.nepjol.info/index.php/JAIM/article/view/14175
DOI: https://doi.org/10.3126/jaim.v4i1.14175

UNDER REVIEW RESEARCHES

  • Knowledge, Attitude and Practice towards COVIOD-19 among Patients with Musculoskeletal and Rheumatic Diseases in Nepal: A Web- based Cross-Sectional Study

            Link: https://www.researchsquare.com/article/rs-24451/v1

            DOI:10.21203/rs.3.rs-24451/v1

  • Study of metabolic parameters in gout: A single center study.
  • Clinicodemographic profile of patients with undifferentiated arthritis.
  • Study of anthropometric parameters in patients with rheumatoid arthritis: THESIS of Ms. Prajwola Prajapati
  • Socio-economic Determinants for Acceptance and Choice of Biological Treatment by Patients with Spondyloarthropathy in Nepal
  • Clinico-demographic Features and Risk Factors for Osteoarthritis in Nepalese Patients: A Cross-sectional Study
  • Late Onset Dipeptidyl Peptidase (DPP)-4 Inhibitor Induced Seronegative Rheumatoid Arthritis: A Case Report from Nepal
  • Knowledge, Attitude and Practice Regarding Diagnosis and Management of Gout among Clinicians: A Report from Web-Based Survey.
  • Study Of Agreement Between Line Immunoassay And Enzyme Linked Immunosorbent Assay For Detection Of Anti-Dsdna Antibodies

ONGOING STUDIES/RESEARCH

  1. Effect of intermittent calorie restriction in BMI
  2. Clinical profile of Psoriatic arthritis patients.
  3. Clinical use and findings of musculoskeletal ultrasound.
  4. Diagnosis of Latent Tubercular infection

In addition, NCRD is also conducting community-based surveys related to the risk-factors, diagnosis and treatment of various rheumatic conditions. We at NCRD can accommodate students from Bachelor in Public Health (BPH) and Bachelor in Pharmacy (B Pharm) interested in conducting clinical thesis as a part of their curriculum.

Thank you for registering for the webinar. We will email you with the webinar login information. Thank you