Study period: October 2020 to March 2021 Inclusion Criteria: Age above 18 years old will be included in the study. Exclusion Criteria: Age below 18 years old and participants who refuse to give informed consent will be excluded. Sample Size: A sample size of 326 in each group (male-female, urban-rural) was calculated based on the estimated population prevalence of 26% the power of the study of 95% and 5% margin of error. Therefore 1304 will be taken as a total sample.  
  Total Male Female Type   Location Sample Size  Status 
Kathmandu 534 276 258 Urban Budanilkantha 275 Completed
Rural Thankot 215 Completed
Sundarijal 44 Completed
Bhaktapur 92 46 46 Urban Bhaktapur 68 Completed
Rural Dadhikot 10 Completed
Balkot 14 Completed
Lalitpur 144 72 72 Urban Imadol 85 Completed
Rural Lubhu 34 Completed
Lele 25 Completed
Dhading 86 39 47 Urban Nilkantha 43
Rural Gajuri 21
Thakre 22
Chitwan 161 24 87 Urban Ratnanagar 126
Rural Darechok 24
Dahakhani 11
Kavre 103 48 55 Urban Dhulikhel 80 Completed
Rural Dolalghat 11 Completed
Dandagaun 12 Completed

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